The Process
The Science behind Endosure
Endometriosis is an inflammatory condition where endometrial tissue produces various inflammatory mediators, including the potent prostaglandins PGE2 and PGF-2𝛼
Prostaglandins are absorbed into the bloodstream and circulate throughout the body, exerting their effects on various tissues. These mediators directly impact the small bowel, regardless of the location of the endometriosis, causing recognizable changes in the gut’s electrical signals.
EndoSure’s use of a tricorder utilises unique technology to record electrical signals from the muscles of the small intestine. It generates a trace known as an EVG, or electroviscerogram, very similar to an ECG, or electrocardiogram, used to assess cardiac wellbeing. The prostaglandins PGE-2 and PGF-2𝛼 are known to cause changes in intestinal motility, resulting in altered electrical activity.
The Endosure tricorder detects the electrical activity, decodes it, and converts it into a visible trace with a unique fingerprint characteristic of endometriosis. It utilizes sophisticated AI clinical decision support software to diagnose endometriosis based on these myo-electric signals.
A 40-minute recording of intestinal myo-electrical pulses using Endosure after drinking a large volume of water is all that’s needed to establish the diagnosis.
This technology, which has been around since the late 1990s and was first published in 1998, has now gained significant recognition in the last 3 years.
Dr. Noar, one of EndoSure’s founders, presented the first paper demonstrating the characteristic EVG changes caused by endometriosis at the American Association of Gynecologic Laparoscopy meeting in 2022. This test is used widely in the USA.
Traditionally, endometriosis testing is extremely hard to diagnose, you may need a Laparoscopy, which is invasive, lengthy, complicated etc. With our new technology we can offer a more accurate diagnosis of endometriosis in just 30 minutes, with a non-invasive procedure.
